Whole-system duct and dryer vent check with before-and-after photos - you see exactly what came out of your vents
That "$99 whole-house special" is a bait ad - the real number appears once they are in your hallway, or the "clean" is a shop-vac at the register. We photograph the inside of your ducts before and after instead.
Trusted Air Quality & Sanitizing for San Antonio Homeowners
Air quality and sanitizing service in San Antonio addresses the mold, bacteria, allergens, and persistent odors that accumulate inside HVAC systems and ductwork after years of cooling-season humidity and pollen cycles. A typical whole-system sanitizing job in San Antonio runs $340-$780 depending on square footage, contamination type, and whether UV light or air purifier installation is included; see our Air Quality & Sanitizing pricing for full details. CleanRun Duct Repair & Cleaning has delivered written-price quotes and documented photo records on every job since 2013, and we’re reachable at (726) 600-7155.
San Antonio’s climate creates a specific problem pattern: eight months of air conditioning run-time pulls outdoor humidity through return vents, and when that moisture hits cooler duct surfaces in unconditioned attics or crawl spaces, it creates the conditions for microbial growth. We’ve photographed this in homes from Alamo Heights to Helotes. The difference between a duct cleaning and a proper sanitizing treatment is whether the crew addresses living contaminants or simply vacuums debris. Our crews use negative-pressure extraction (suction that contains dust and spores so they don’t re-enter the home) followed by EPA-registered treatments applied to the full plenum (the central distribution box where all duct runs connect). Every step is photographed, and the written scope is delivered before any panel comes off.
Tomas Reyes established CleanRun in 2013 after seeing too many San Antonio homeowners pay for “sanitizing” that amounted to a scented spray at the register. Our approach is different: Haven Standard Clause 1 requires a written price before work starts, and Haven Standard Clause 5 requires the Documented Photo Record. We’ve served over 52,000 homes, and every one has those two deliverables in its file.
What Our Air Quality & Sanitizing Service Includes
Mold Treatment
Mold in HVAC systems typically appears as dark spotting on the plenum interior or musty odor that returns within 48 hours of standard duct cleaning. San Antonio’s combination of high outdoor humidity and attic temperatures 30-40 degrees above ambient creates condensation points that feed mold colonies in roughly 15% of the homes we inspect in Terrell Hills and Castle Hills. Our mold treatment begins with mechanical removal using Rotobrush contact cleaning on every duct run surface, followed by EPA-registered antimicrobial application to the plenum and trunk lines. We photograph the colony location, the post-treatment surface, and the moisture source we identified so you have a record of what was found and how it was addressed.

Bacteria Sanitizing
Bacterial contamination in ductwork doesn’t produce visible mold but can generate the sour or “locker room” odor that persists after standard cleaning, particularly in homes with pets or where the HVAC system sat idle during a vacancy. We treat bacterial loads with a fogging application of Guardsman-sourced sanitizer distributed through the duct system under negative pressure, ensuring the product reaches branch lines past the first elbow where debris accumulates. The treatment is documented with before-and-after swab results when visibly heavy contamination is present, and the written scope specifies which registers received focused application.

Odor Removal
Persistent HVAC odors in San Antonio homes usually trace to one of three sources: pet dander baked onto heat exchanger surfaces during heating season, rodent activity in attic trunk lines, or previous water intrusion that left organic material in the plenum. Our odor removal process isolates the source register by register using a borescope camera (a flexible inspection camera fed through the duct), then applies targeted treatment rather than masking agents. In Kirby and Windcrest, we’ve found that odors attributed to “dirty ducts” often originate in the evaporator coil pan, which we inspect and include in the photo record even when the customer called for ductwork treatment.

UV Light Installation
UV-C light installed at the evaporator coil or in the return plenum interrupts mold and bacteria reproduction by damaging cellular DNA, providing continuous protection between professional treatments. We install Honeywell and Abatement Technologies UV systems sized to the airflow rate of your specific unit, not generic wattage recommendations. The installation includes a written performance specification (light intensity at the coil surface, bulb replacement interval, and warranty terms) and photographs of the mounting location so future service crews know what they’re working with. Most Air Quality & Sanitizing - Universal City and Live Oak installations we perform use 18-36 watt systems depending on tonnage.

Air Purifier Install
Whole-home air purifiers integrate with existing HVAC ductwork to filter or neutralize particles and organisms at the system level rather than relying on portable units that only treat single rooms. We install Aprilaire and Honeywell media purifiers and electronic air cleaners, selecting the model based on your home’s square footage, existing duct static pressure, and specific concerns (allergen load, pet dander, wildfire smoke from seasonal agricultural burning). Every installation quote includes the written price for the unit, electrical connection if required, and any duct modification needed for proper airflow, with no per-vent add-ons.

Allergen Reduction
San Antonio’s allergen profile is distinct: mountain cedar pollen in winter, oak and pecan in spring, and sustained grass pollen through summer create a cumulative load that standard fiberglass filters don’t capture. Our allergen reduction service combines HEPA-level negative-pressure extraction of existing deposits with treatment of the full duct run, then specifies the correct filter MERV rating (Minimum Efficiency Reporting Value, a standardized measure of particle capture) for your system without overloading the blower motor. In Leon Valley and Air Quality & Sanitizing in Converse, we’ve documented cases where homeowners had upgraded to MERV 13 filters without checking static pressure, causing coil freeze-ups that actually increased humidity and mold risk.

What happens when you call
- 1
A real person answersNo phone trees - you reach a local pro.
- 2
You get an upfront price rangeHonest numbers before anyone is dispatched.
- 3
A background-checked tech heads outLicensed & insured, dispatched right away.
- 4
You approve before work beginsNothing starts until you say go.
Signs You Need Air Quality & Sanitizing Right Now

- Musty or sour odor when the AC first cycles on. This indicates microbial growth on the evaporator coil or in the plenum, not just “stale air.” The smell is metabolites from active bacteria or mold, and it will intensify as the colony expands. In San Antonio’s cooling-dominant climate, we see this most often in homes where the system oversized for the square footage, causing short cycles that don’t fully dehumidify the coil.
- Visible dark spotting on register vents or surrounding ceiling. These stains are often mistaken for dust accumulation, but when they reappear within weeks of cleaning, they indicate mold spores being pushed through the system and depositing at the supply point. The correct response is treating the source in the ductwork, not repeatedly wiping the register.
- Allergy symptoms that worsen at home and improve away from the house. This pattern suggests the HVAC system is distributing a concentrated allergen load rather than the general outdoor pollen exposure you’d encounter elsewhere. We’ve traced this to rodent debris in attic trunk lines, post-construction drywall dust still in branch ducts, or mold in the plenum of homes in Selma and Helotes built during the 2019-2021 construction surge.
- Recent water intrusion or roof leak, even if “fixed.” Ductwork in contact with wet insulation wicks moisture into the system, and the dark interior of a duct run maintains humidity long after the visible leak is repaired. San Antonio’s clay tile and composition shingle roofs both produce this pattern when flashing fails at valley intersections.
- System has never been sanitized, only “cleaned.” Standard duct cleaning removes loose debris but doesn’t address microbial growth or bacterial biofilm adhered to duct surfaces. If your last service didn’t include photographic documentation of the plenum interior and a written treatment specification, you likely received debris removal without sanitizing.
Before
AfterOur Air Quality & Sanitizing Process - Step by Step
- 1
Written price delivered before work starts. Haven Standard Clause 1: we inspect your system, identify the contamination type and extent using borescope photography, and deliver a written price for the complete scope. No per-vent add-ons, no “once we’re in there” surprises. The price covers the full system, and you approve it before any panel comes off.
- 2
Containment and negative-pressure setup. We seal registers and establish negative-pressure extraction at the plenum so dislodged contaminants are captured rather than redistributed through your home. This is standard for our crews using Nikro equipment, not an upgrade or optional step.
- 3
Mechanical removal and contact cleaning. Every duct run receives physical agitation using Rotobrush contact cleaning heads sized to the duct diameter, followed by vacuum extraction. The plenum and trunk lines are hand-cleaned or power-brushed depending on contamination type. We photograph every surface before and after.
- 4
Targeted sanitizing treatment. Based on what the inspection found, we apply EPA-registered antimicrobial, bacterial sanitizer, or odor neutralizer as specified in your written scope. UV light or air purifier installation occurs at this stage if included, with electrical connections made to code and photographed.
- 5
Documentation delivery and 365-Day Done Right Promise. You receive the complete photo record showing inside every duct run, the written scope completed, and the warranty terms. If anything in the work is not right, we make it right, backed in writing, not subject to manager discretion.
How Much Does Air Quality & Sanitizing Cost in San Antonio?

A typical bacteria sanitizing or odor removal treatment for a single-system home in San Antonio runs $340-$520. Mold treatment requiring mechanical removal and antimicrobial application ranges $480-$780 depending on plenum accessibility and whether attic trunk lines are involved. UV light installation adds $280-$440 for the unit and electrical connection. Whole-home air purifier installation ranges $520-$1,180 depending on the Aprilaire or Honeywell model selected and any duct modification required for proper static pressure.
Several factors move the price within these ranges. Homes in Alamo Heights and Terrell Hills with original 1950s-1970s ductwork often have smaller access panels and more rigid fiberboard construction, increasing labor time. Two-system homes require separate treatment of each unit and plenum. Contamination that has reached the evaporator coil or blower assembly adds scope beyond ductwork alone, which we identify during inspection and specify in the written price.
The most common overpayment we see is the $79-$149 “sanitizing special” that covers a single register or a scented spray application with no mechanical removal. Real sanitizing requires accessing the full duct system and plenum, which takes 3-5 hours for a typical San Antonio home. If a quote seems low, ask what equipment will be used, whether every duct run will be photographed, and whether the price is fixed or subject to per-vent add-ons.
CleanRun’s estimate is free and includes the full inspection with borescope photography. We put our written price next to any competitor’s written estimate under Haven Standard Clause 2: Free Second Opinion. Call (726) 600-7155 to schedule.
Air Quality & Sanitizing Near San Antonio - Our Service Area
CleanRun crews complete air quality and sanitizing work throughout Bexar County and adjacent communities, with same-week scheduling typical for Air Quality & Sanitizing in San Antonio proper and the near suburbs. We regularly treat homes in Air Quality & Sanitizing in Alamo Heights and Air Quality & Sanitizing in Castle Hills, where older construction and mature tree cover create distinct mold and allergen profiles. Service to Terrell Hills, Leon Valley, Kirby, Windcrest, Helotes, Live Oak, Converse, Universal City, and Selma is scheduled from our central San Antonio base. Drive time to outlying areas is built into the written price, not added as a trip charge after arrival.
Serving San Antonio, TX - Our Local Coverage Area

We’re based in the San Antonio area and know this community well. Use the map below to see our service coverage - if you’re nearby, we can almost certainly help.
Frequently Asked Questions - Air Quality & Sanitizing in San Antonio
Air Quality & Sanitizing - San Antonio treats living contaminants, mold, bacteria, and persistent odors inside the HVAC system using EPA-registered products and mechanical removal, while standard duct cleaning removes loose debris and dust. Duct cleaning improves airflow and reduces particulate load; sanitizing addresses the microbial sources of odor, allergy symptoms, and recurring contamination. We photograph the difference so you can see whether your last service addressed both or only one. Call (726) 600-7155 for an inspection that identifies which your system needs.
A typical single-system sanitizing treatment takes 3-5 hours including setup, mechanical cleaning of every duct run, application, and documentation. Mold treatment or multi-system homes may extend to 6-8 hours. We schedule the arrival time, not a window, and the written scope specifies the expected duration so you can plan accordingly. The job isn’t complete until you’ve received the photo record and written documentation.
Most San Antonio homeowners pay $340-$780 for complete sanitizing treatment depending on system size, contamination type, and whether UV or air purifier installation is included. We deliver the exact written price after inspection, before any work starts, with no per-vent add-ons. Bring any competitor’s written estimate and we’ll put our number next to it at no cost under Haven Standard Clause 2. Call (726) 600-7155 for a free estimate.
Yes. We install and service Honeywell UV and air purifier systems, Aprilaire whole-home purifiers, and Abatement Technologies equipment, and we stock replacement bulbs and media for models commonly found in San Antonio homes. Our crews carry the manufacturer specifications for proper sizing and static pressure compatibility. If you have a different brand or aren’t sure what’s installed, we’ll identify it during inspection and specify the correct service in writing.
We don’t use emergency pricing or urgency framing for scheduled sanitizing work. Severe mold or odor issues that affect habitability are prioritized for next-available scheduling, and all calls are answered by a live person who can assess whether temporary measures (isolation of the affected system zone) are appropriate until the crew arrives. The inspection and written price come first; no work starts without your approval of the scope.
Every job is backed by the 365-Day Done Right Promise: if the work is not right, CleanRun makes it right, in writing, with no manager approval required. Specific treatments carry additional manufacturer warranties: Honeywell and Aprilaire UV bulbs are warranted for their rated lifespan, and Guardsman antimicrobial applications carry a 12-month retreatment guarantee against recurrence at the treated location. All terms are specified in your job documentation, not referenced vaguely in marketing copy.
Clear a 3-foot area around the indoor HVAC unit and ensure attic or crawl space access is unobstructed if your ductwork runs through those spaces. Pets should be secured away from the work area. You don’t need to clean or vacuum beforehand; our containment setup handles dust control. We’ll need access to electrical outlets for our negative-pressure equipment. The crew will identify themselves by name before arrival, in uniform, and will review the written scope with you before starting.
Schedule Your Air Quality & Sanitizing Service in San Antonio Today

Call (726) 600-7155 to speak with a live person and schedule your free inspection. You’ll receive a written price before any work starts, a Documented Photo Record of every duct run when the crew leaves, and the 365-Day Done Right Promise in writing. No per-vent pricing, no coupon bait-and-switch, just documented results you can verify.
Written by Tomas Reyes, Owner at CleanRun Duct Repair & Cleaning, serving San Antonio since 2013.




Before
After
Before
After